Course Title : Short Course on Clinical & Epidemiological Research Study Design

Duration: 17 Jun, 2019 - 19 Jun, 2019

Hosted by : icddr,b

Published On : 14 May, 2019

Close Date : 29 May, 2019

Location : Seminar Room-1, Sasakawa International Training Centre, icddr,b, Dhaka, Bangladesh View Detail

Prof. Zuo-Feng Zhang, UCLA who will be visiting Dhaka to participate in the Scientific Advisory Group Review (SAG) has offered to give a short course on Clinical and Epidemiological Research Study Design at icddr,b from 17 – 19 June 2019.


This course comes with my full endorsement since it offers unparalleled access to first-class training.  Scientists from ALL divisions will benefit from the methods coaching covered in these sessions. Although the course focuses on cancer epidemiology scientists are strongly recommended to attend to improve their technical ability and benefit from the experience and guidance of Professor Zhang whose methods are suitable for all disciplines.


Course Description


To introduce students to basic concept in clinical epidemiological study design, including hypothesis generating, retrospective and prospective study designs including cohort, nested case-control, case-cohort and case-control studies, causation, bias, confounding and interactions  




June 17 (Monday)

June 18 (Tuesday)

June 19 (Wednesday)


Hypothesis generating and Testing

Study Design

Observational Studies

Study Design: Bias, Confounding           

9:40 -11:30

Causation and Cancer Epidemiology

Study Design: Experimental Studies

Study Design: interaction






June 17 (Monday)


8:00-9:30        Hypothesis generating and testing

                        -Observation the patterns of human cancer

-Generate hypothesis


Ref:     Peto J. Cancer epidemiology in the last century and the next decade. Nature.

            2001 May 17;411(6835):390-5. Review. PubMed PMID: 11357148.


9:40-11:30      Causation and Cancer Epidemiology


Ref:     Goodman SN and Samet J. Cause and Cancer Epidemiology. In Schottenfeld D and Fraumeni JF Jr. Edits. Cancer Epidemiology and Prevention. Oxford University Press, New York, 2006, pp 3-9.   


June 18 (Tuesday)


8:00-9:30        Cancer Epidemiology Study Design: Observational Studies

                        -Design and conduct a study to test hypothesis

                        -Interpretation of results

                        -Criteria of causality


Ref.:                Lagiou P, Trichopoulos D, and Adami HO. Concepts in Cancer Epidemiology and Etiology. In Text Book of Cancer Epidemiology (Editors: Adami HO, Hunter D, and Trichopoulos D). Oxford, University Press, 2008, pp127-154.


                        Chen Z, Chen J, Collins R, Guo Y, Peto R, Wu F, Li L; China Kadoorie Biobank

                        (CKB) collaborative group. China Kadoorie Biobank of 0.5 million people: survey methods, baseline characteristics and long-term follow-up. Int J Epidemiol. 2011 Dec;40(6):1652-66. doi: 10.1093/ije/dyr120. Epub 2011 Sep 21. PubMed PMID: 22158673; PubMed Central PMCID: PMC3235021.


                        Zhao JK, Wu M, Kim CH, Jin ZY, Zhou JY, Han RQ, Yang J, Zhang XF, Wang XS, Liu AM, Gu X, Su M, Hu X, Sun Z, Li G, Li L, Mu L, Zhang ZF. Jiangsu Four Cancers Study: a large case-control study of lung, liver, stomach, and esophageal cancers in Jiangsu Province, China. Eur J Cancer Prev. 2017 Jul;26(4):357-364. doi: 10.1097/CEJ.0000000000000262. PubMed PMID: 27275735.


9:40-11:30      Cancer Epidemiology Study Design: Experimental Studies


June 19 (Wednesday)


8:00-9:30        Study Design: Bias, Confounding


9:40-11:30      Interaction assessment



Suggested Text Book:


Adami HO, Hunter D  and Trichopoulos D. Text Book of Cancer Epidemiology. Oxford, University Press, 2008


Instructor: Zuo-Feng Zhang, M.D., Ph.D.

Professor of Epidemiology and Medicine

UCLA Fielding School of Public Health